• Evsyukov, V., Domanskyi, A., Bierhoff, H., Gispert, S., Mustafa, R., Schlaudraff, F., Liss, B., and Parlato, R. (2017). Genetic mutations linked to Parkinson’s disease differentially control nucleolar activity in pre-symptomatic mouse models. Dis Model Mech. pii: dmm.028092. doi: 10.1242/dmm.028092. [Epub ahead of print]
  • Schnöder, T.M., Eberhardt, J., Koehler, M., Bierhoff, H.B., Weinert, S., Pandey, A.D., Nimmagadda, S.C., Wolleschak, D., Johrens, K., Fischer, T., et al. (2017). Cell autonomous expression of CXCL-10 in JAK2V617F-mutated MPN. J Cancer Res Clin Oncol 143, 807-820.
  • Zhao, Z., Dammert, M.A., Hoppe, S., Bierhoff, H., and Grummt, I. (2016). Heat shock represses transcription of rRNA genes by inactivation of TIF-IA and lncRNA-dependent changes in nucleosome positioning. NAR, pii: gkw496. [Epub ahead of print].
  • Zhao, Z., Dammert, M.A., Grummt, I., and Bierhoff, H. (2016). LncRNA-induced nucleosome repositioning reinforces transcriptional repression of rRNA genes upon hypotonic stress. Cell Rep, 14, 1876-1882.
  • Parlato, R., and Bierhoff, H. (2015). Role of nucleolar dysfunction in neurodegenerative disorders: a game of genes? AIMS Molecular Science, 2(3): 211-224.
  • Bierhoff, H. (2014). Stichwort: Nicht-codierende RNA. Naturw Rdsch, 67/12. (Research Monograph)
  • Bierhoff, H., Dammert, M.A., Brocks, D., Dambacher, S., Schotta, G., and Grummt, I. (2014). Quiescence-induced lncRNAs trigger H4K20 trimethylation and transcriptional silencing. Mol Cell, 54: 675-682.
  • Bierhoff, H., Postepska-Igielska, A., and Grummt, I. (2013). Noisy silence: Non-coding RNA and heterochromatin formation at repetitive elements. Epigenetics, 9: 53-61.
  • Kiryk, A., Sowodniok, K., Kreiner, G., Rodriguez-Parkitna, J., Sonmez, A., Gorkiewicz, T., Bierhoff, H., Wawrzyniak, M., Janusz, A.K., Liss, B., et al. (2013). Impaired rRNA synthesis triggers homeostatic responses in hippocampal neurons. Front Cell Neurosci, 7: 207.
  • Kreiner, G.*, Bierhoff, H.*, Armentano, M., Rodriguez-Parkitna, J., Sowodniok, K., Naranjo, J.R., Bonfanti, L., Liss, B., Schutz, G., Grummt, I., et al. (2013). A neuro-protective phase precedes striatal degeneration upon nucleolar stress. Cell Death Differ, 20: 1455-1464.
    * equal contribution
  • Bierhoff, H., Schmitz, K., Maass, F., Ye, J., and Grummt, I. (2010). Noncoding transcripts in sense and antisense orientation regulate the epigenetic state of ribosomal RNA genes. Cold Spring Harb Symp Quant Biol, 75: 357-364.
  • Hoppe, S., Bierhoff, H., Cado, I., Weber, A., Tiebe, M., Grummt, I., and Voit, R. (2009). AMP-activated protein kinase adapts rRNA synthesis to cellular energy supply. Proc Natl Acad Sci U S A, 106: 17781-17786.
  • Bierhoff, H., Dundr, M., Michels, A.A., and Grummt, I. (2008). Phosphorylation by casein kinase 2 facilitates rRNA gene transcription by promoting dissociation of TIF-IA from elongating RNA polymerase I. Mol Cell Biol 28, 4988-4998.
  • Mayer, C., Bierhoff, H., and Grummt, I. (2005). The nucleolus as a stress sensor: JNK2 inactivates the transcription factor TIF-IA and down-regulates rRNA synthesis. Genes Dev, 19: 933-941.
  • Arabi, A., Wu, S., Ridderstrale, K., Bierhoff, H., Shiue, C., Fatyol, K., Fahlen, S., Hydbring, P., Soderberg, O., Grummt, I., et al. (2005). c-Myc associates with ribosomal DNA and activates RNA polymerase I transcription. Nat Cell Biol, 7: 303-310.
  • Pawlowski, A., Riedel, K.U., Klipp, W., Dreiskemper, P., Gross, S., Bierhoff, H., Drepper, T., and Masepohl, B. (2003). Yeast two-hybrid studies on interaction of proteins involved in regulation of nitrogen fixation in the phototrophic bacterium Rhodobacter capsulatus. J Bacteriol, 185: 5240-5247.


Research Monographs

  • Bierhoff, H. (2014). Stichwort: Nicht-codierende RNA. Naturw. Rdsch. 67/12.

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